Although I haven’t read the exact studies and what they base their parameters for success on, it appears that Zamboni’s procedure to open up venous drainage in the brain is working fairly well. One of the problems I have with stenosis (which is what Zamboni’s procedure attempts to correct) causing MS is that it fails to explain the peculiar demographics associated with MS. His explanation as to the cause of the lesions is likewise lacking but that’s an entirely different subject.
MS is not an equal opportunity condition. Not only is it selective about the areas of the brain and cord it targets, but it also shows gender, geographical and racial biases. That is, people living in southern climates have a lower incidence of MS than those living in northern climates and the incidence of MS in tropical climates is very low. But if you move a child from a northern to a southern climate their incidence drops to match the level of those of the southern climate. On the other hand, moving adults to southern climates has no impact on incidence.
Oddly enough, many adults with MS claim to feel better at higher altitudes where the weather is colder and more similar to northern latitude climates, but the effects of gravity is less and barometric pressure is lower and more similar to southern latitude climates. It seems that the higher MS patients go, the better they feel. This is interesting because northern latitudes are associated with cold air masses and higher barometric conditions. Conversely, higher altitudes are associated with lower barometric pressure.
The most peculiar aspect about MS, however, is that Asians have a very low incidence of MS regardless of where they live, and Eskimos living in even the most extreme northern climates never get MS. Does this mean that people living in tropical and southern climates, Asians and Eskimos have a lower incidence of venous stenosis? This is highly doubtful.
Rather than venous stenosis per se, it is my opinion that gender and racial differences are probably related to design issues in the skull due to upright posture that can affect venous drainage. The higher incidence of MS in northern climates are associated with a much greater probability of winter related whiplash type trauma that can injure and subsequently impact venous drainage outlets in the base of the skull and upper cervical spine.
In this regard, studies continue to show a highly suspicious connection between MS and trauma, as well as dementia and Parkinson’s in adults. It’s just common sense that young people are more susceptible to whiplash type traumas to the head and neck while the bones, brain and cord are still growing.
In addition to venous drainage issues, I also discuss the bigger picture of cranial hydrodynamics and the likely role of upright posture and the design of the skull, spine and circulatory system of the brain in neurodegenerative diseases in my book The Dowside of Upright Posture – The Anatomical Causes of Alzheimer’s, Parkinson’s and Multiple Sclerosis.